Susanna White was pregnant when she traveled on Mayflower and delivered her second son, Peregrine, while the ship was anchored on Cape Cod. Her husband William and their servants died during the first winter.

Susanna later married fellow passenger Edward Winslow, who was also widowed during the first winter, in the first marriage in Plymouth Colony. She and Edward had 5 children together. She died between 1654 and 1675 and is buried in Winslow Cemetery in Marshfield, Massachusetts.